Adolescents and youth are a key population for reproductive health (RH) interventions, because young people suffer disproportionately from negative RH outcomes, including acquisition of HIV and other sexually transmitted infections; unintended, unwanted, or mistimed pregnancy; unsafe abortion; and gender-based violence. Effective monitoring and evaluation (M&E) of RH interventions designed for adolescents and youth is essential to determine their success and impact and show where improvement is needed. MEASURE Evaluation, which is funded by the United States Agency for International Development, conducted the research presented in this report to identify gaps in the M&E of adolescent and youth reproductive health (AYRH) programs. This process consisted of reviewing the landscape of M&E of AYRH interventions, outcomes, and impacts; identifying measurement gaps; and making recommendations to improve the M&E of AYRH activities and programs across a spectrum of RH categories.