Acquired Immune Deficiency Syndrome (AIDS) is a tragedy of devastating proportions in sub-Saharan Africa. In Kenya, the cumulative number of deaths due to HIV/AIDS may rise to 2.6 million by the end of 2005 if no interventions are introduced. Most AIDS death occur between the ages of 25 and 35. This has resulted into serious socio-economic impact, particularly in Universities. It is for this reason that the Africa America Institute (AAI) in collaboration with its partners the Association of African Universities (AAU) and the Working Group on Higher Education (WGHE) of the Association for the Development of Education in Africa (ADEA) decided to undertake case studies on the impact of HIV/AIDS on individual universities in 12 Global Aids Initiative countries (Kenya, Botswana, Ivory-Coast, Ghana, Zambia, Ethiopia, Mozambique, Namibia, Nigeria, Rwanda, South Africa, and Tanzania) and to document the responses and HIV/AIDS management strategies adopted by Universities in these countries. The aim of this case study was to inventory the Policies and strategies that 8 selected Kenyan universities (Kenyatta, Nairobi, Maseno, Jomo Kenyatta University of Agriculture and Technology, Catholic, Kabarak, Moi and Western University college) have developed to address the HIV/AIDS pandemic. The study has critically looked at how these universities have responded to HIV/AIDS, with respect to administrative policies, academic programmes, and involvement with national policy and community based organizations. This report also presents the main findings and recommendations on the impact of HIV/AIDS on selected universities. The study was of a descriptive nature and relied mostly on qualitative methodologies such as personal interviews, group discussions and the analysis of existing documents.