The Our Rights, Our Lives, Our Future (O3) programme, implemented by UNESCO, has a vision of a sub-Saharan Africa (SSA) where all adolescents and young people (AYP) attain positive health, education, and gender equality outcomes. Through its flagship programme UNESCO supports countries to provide good quality comprehensive sexuality education that empowers adolescents and young people while developing the skills, knowledge and attitudes they need to prevent HIV infections, reduce early and unintended pregnancies, and eliminate gender-based violence. It also focuses on building safe learning environments for learners by preventing all forms of violence including bullying in and around schools. To assess the programme’s successes, learnings and best practices and to inform future programmes, UNESCO commissioned this final evaluation to the KIT Royal Tropical Institute. The final evaluation entailed ten qualitative country case studies; 15 key informant interviews at the global and regional levels; secondary data analysis of large-scale household surveys and a document review covering 33 countries in SSA. In eight of the case study countries, focus group discussions (FGDs) with AYP/learners, parents and teachers were conducted. In all case study countries, key informant interviews with policy/decision-makers, programme implementers, traditional and religious leaders, SRH service providers, representatives from parent-teacher associations (PTAs) and training institutions were conducted. The total number of participants in the ten countries was 436.