The Symposium "Working on HIV and AIDS in education: System and workplace responses for and by education sector workers" took place in Brussels, Belgium on 2 December 2010. The Symposium was convened by the UNAIDS Inter-Agency Task Team (IATT) on Education and preceded the UNAIDS IATT on Education's members meeting on 3 December 2010. Education International (EI) and International Labour Organization (ILO) co-hosted the Symposium. The symposium aimed to encourage stronger dialogue about the workplace response at institutional and school levels, in order to ensure that workplace policies have greater impact and are better integrated in overall sectoral planning. Specifically, the Symposium provided a forum to advance the discussion of workplace policies and programmes to respond to HIV and AIDS, with in-depth analysis and discussion of the following issues: the coverage, quality and implementation status/effectiveness of existing workplace policies; the impact of policies on prevention and mitigation outcomes for schools, universities and training sites; effective ways to mainstream workplace HIV and AIDS policies and implementation into sectoral plans and strategies where this approach is judged to be the most effective; obstacles to the meaningful participation of education sector workers in policy development and implementation; and system level implications of the HIV and AIDS response, beyond individual level impacts. The Symposium participants comprised of members of the UNAIDS IATT on Education, representatives of bi-lateral and multi-lateral organizations, governmental and non-governmental institutions (NGOs) as well as civil society orgnaizations. This report synthesizes the key issues discussed at the Symposium and the conclusions reached.