This chapter in ‘All means all! OpenTextbook for diversity in education’ deals with inclusive teaching methods and assessment in Comprehensive Sexuality Education (CSE). In this chapter you will find the answers to the following questions: 1) What is Comprehensive Sexuality Education (CSE) and how does it differ from traditional or faith-based approaches to sexuality education? 2) What are the key components of CSE, and how do they address the cognitive, emotional, physical, and social aspects of sexuality? 3) How does a rights-based approach underpin CSE and contribute to empowering young people to make informed decisions? 4) In what ways does CSE cater to diverse learners, including those with different cultural backgrounds, gender identities, and special educational needs? 5) What common myths about sexuality education does CSE challenge, and how does it foster a safe and inclusive learning environment?