In response to COVID-19, countries around the world have implemented several public health and social measures (PHSM), such as movement restrictions, closure of schools and businesses, and international travel restrictions. As the local epidemiology of the disease changes, countries will adjust (i.e. loosen or reinstate) these measures according to the intensity of transmission. WHO has issued guidance on adjusting PHSM while managing the risk of resurgence of cases. A series of annexes has been developed to help guide countries through adjusting various public health measures in different contexts. This annex provides considerations for decision-makers and educators on how or when to reopen or close schools in the context of COVID-19. These decisions have important implications for children, parents or caregivers, teachers and other staff, communities, and society at large. This document was drafted based a review of available literature, discussion with experts, regional partners and country examples.