This study aimed to evaluate the effectiveness of health education initiatives to increase knowledge and improve attitudes and behaviors in response to rising HIV incidence. In this study, 223 students who received comprehensive health education were compared to 217 control group students who did not receive this education. Results showed that after the intervention, intervention students had better knowledge of HIV transmission and prevention, were less likely to see AIDS as a "white man's disease," were more likely to be tolerant of people living with HIV and AIDS, reported fewer sexual partners, reportedáincreased consistent condom use and condom use at last intercourse. This study showed health education to be effective in improving knowledge, attitudes and sexual behaviors.