UNICEF and UNAIDS launched the ALL IN platform in February 2015 to galvanize global action towards HIV and a population that were largely neglected in the global AIDS response – adolescents. The ALL IN initiative, with a focus on 25 lead countries that contribute to 86 per cent of all new HIV infections in adolescents, seeks to bring adolescents into focus in fast-track efforts to end the AIDS epidemic by 2030, and provides three targets for the year 2020 to frame this acceleration agenda: 1. Reduce new HIV infections among adolescents by at least 75 per cent; 2. Reduce AIDS-related deaths among adolescents by at least 65 per cent; 3. End stigma and discrimination. The purpose of the report is to showcase the significant contributions of many partners to research, innovations, community mobilization, programmes and policy actions aimed at ending the AIDS epidemic in adolescents in support of the ALL IN! agenda.