The toolkit aims to assist education sector staff, networks of people living with HIV, and others to apply the principles for the greater involvement of people living with or affected by HIV and AIDS (GIPA) in a comprehensive approach for the education sector's response to HIV and AIDS. The toolkit includes 10 activities, each requiring from 1 to 3 hours, which can be modified as needed. The activities introduce the basics of HIV and AIDS, the concept of GIPA, and ways its principles can be incorporated into a comprehensive approach for the education sector's HIV and AIDS initiatives. It includes capacitybuilding activities focused on advocacy skills. The issues surrounding stigma and discrimination, as well as confidentiality and disclosure, are addressed via case studies and role plays. These activities can help to create a supportive and enabling environment. Programme planning activities to operationalise the principles of GIPA include identifying partners, conducting a resource gap analysis, mobilising resources, and action planning. This toolkit includes step-by-step lesson plans, handouts, and facilitator resources for each activity, with additional tips for individuals conducting the activities. Suggestions for monitoring and evaluation, with corresponding sample quizzes, are offered at the conclusion of each activity and at the end of the toolkit, to help users develop a more long-term approach to evaluation. The document closes with several appendices, including a glossary, guidelines for facilitators, and detailed descriptions of earlier models for a comprehensive approach in the education sector's response to HIV and AIDS.