This study was undertaken to identify the HIV prevention programmes and practices that have been implemented at HEIs and the extent to which they cohere with good practice as described in the literature. The research team began by identifying “international and local good practice with regards to HIV/AIDS prevention”. The outcome of this process informed the development of an HIV/AIDS Prevention framework with clear indicators to guide the design, development and implementation of effective HIV/AIDS Prevention interventions/programmes appropriate for students in the higher education sub-sector. Next, the study team applied this instrument to a selected number of HEIs to identify and review good practices that had been adopted. Findings from this research project would be used to “inform the development and implementation of appropriate, innovative and effective HIV/AIDS Prevention strategies for the sub-sector”. By identifying and documenting good practices at some universities and disseminating those practices to, or sharing them with, other universities, the overall quality of prevention efforts across HEIs could be improved. In addition, the study helps to highlight the wider role of HEIs in national control efforts.