This document was published by the Education Development Centre in collaboration with UNICEF, CARICOM and Health and Family Life Education (HFLE) coordinators and teachers from four CARICOM countries: St. Lucia, Grenada, Barbados and Antigua. The purpose of this manual is to provide regional coordinators from CARICOM countries with materials and resources to conduct in country teacher-training on two unit themes in the HFLE Common Curriculum: self and Interpersonal Relationships and Sexuality and Sexual Health. These two units aim to achieve measurable gains in student's knowledge, health-promoting attitudes and skills and reductions in risk behaviours related to HIV, STI, unintended pregnancy and violence. The contents of this manual include the following: seven sessions designed to increase teacher's knowledge and skills for implementing life skills education, and, specifically, the HFLE curriculum lessons, in their classrooms; background resources and information for trainers on HFLE, life skills education and teaching methods used to teach life skills, including materials on behavioural theories supporting life skills education, strategies, for establishing a respectful classroom atmosphere when teaching life skills, and alternative assessment methods. This manual does not focus on HIV & AIDS: this theme is not integrated into the manual.