Recognizing the importance of teachers in stopping the spread of HIV/AIDS in Zambia, the Ministry of Education requires that HIV/AIDS be integrated into classroom teaching at all levels. MOE, along with many partners, are implementing in-service training for teachers to give them the skills to do this. However, in order to be sustainable, HIV/AIDS needs to be an integral part of the COE curriculum. A survey of COE student-teachers and staff conducted by MOE and CHANGES2 in 2006 showed that student-teachers do not feel comfortable or well-prepared to teach HIV/AIDS prevention in the classroom. All those interviewed said that HIV/AIDS Education should be part of the COE curriculum. Based on this information, MOE has been working closely with college Tutors, student-teachers and Teacher Education and Specialized Services in MOE to develop an HIV/AIDS Teacher Education Course (HATEC). This draft Handbook was designed for student-teachers to use as they move through the HATEC. It includes activities which the tutor may do in the class. Also, it can be used by teachers in their classrooms.