Information, education and communication are the avenues that can be used to inform people about the spread, impact and prevention of HIV/AIDS. Through the assistance of the NAC, Manus has been fortunate in the delivery of health promotion on HIV/AIDS via these different avenues and by targeting different audiences. For instance, every year the town schools participate in celebrating the World AIDS day and theatre groups perform in schools with funds allocated for by the Provincial AIDS office. This study is aimed at evaluating the effectiveness of health promotion on HIV/AIDS in rural and urban schools in Manus Province. It is a quantitative cross-sectional study involving 259 students from 13 schools; 4 urban and 5 rural TopUp schools, 2 high schools and 2 secondary schools. The objectives of this study are; to assess the student's knowledge and perception of HIV/AIDS and the impact of this knowledge, and to identify sources of information in regard to this incurable disease. This study has indicated that students are very much aware of HIV/AIDS and have been informed through different avenues. However, the results show that students lack some vital information on HIV/AIDS. This could be due to lack of in-depth knowledge about HIV/AIDS by those who disseminate information or that students have not been given proper education on some aspects of the disease. In areas where other sources are inaccessible, the use of local theatre groups and the distribution of IEC materials on HIV/AIDS have proven to be an effective means of educating the community and in particular the school children.