This final report of a reproductive health project for adolescents in 4 villages in the district of Penjikent (north-western Tajikistan) summarizes 12 months of activities conducted from May 2009 to April 2010. The purpose of our engagement was to help Tajik youth to achieve sexual and reproductive good health, an issue also widely addressed in many other countries and promoted by the World Health Organization. We focused on implementing three objectives in the rural villages of Shingak, Zidde, Ravoj and Roj, all part of the Penjikent district: 1) Improve the capacity of local partners from the Ministry of Health (MoH) and the Ministry of Education (MoE) to understand adolescent reproductive health (RH) needs, attitudes, and current practices, including the adolescents' preferred sources of RH information and care; 2) Enhance the ability of local government providers (MoH and MoE) to provide quality and youth-friendly reproductive health and life skills counselling services; 3) Raise awareness and correct misinformation among local social networks (parents, clubs, and key influential leaders) about youth concerns on RH, HIV/AIDS, sexually transmitted infections (STI) and general life skills.