This document is a report of the international workshop on the development of empowering educational HIV/AIDS prevention strategies and gender sensitive materials (not specific for school use), organised in Nairobi, Kenya by the UNESCO Institute for Education in collaboration with the Southern Africa AIDS Information Dissemination Service. It brought together about 25 representatives from governments, NGOs and regional agencies active in HIV/AIDS prevention work and those involved in the formulation of educational strategies and/or development of information, education and communication materials. Participants represented seven regional countries (Botswana, Kenya, South Africa, Uganda, Zambia and Zimbabwe). Building on their experiences and expertise in the prevention field, the participants concentrated on two different but interrelated topics:- 1) Development of empowering prevention strategies with a focus on gender issues; 2) elaboration of guidelines for the production of gender-sensitive materials. Participants also identified relevant gender issues that affect prevention work and elaborated strategies to tackle them effectively, resulting in principles of empowering prevention strategies. Proposals for the production of a set of gender-sensitive materials were elaborated and a preliminary action plan was laid down concerning the procedures and responsibilities for subsequent production and dissemination of materials. The report contains the following main sections:- 1) Overview of experiences/projects on HIV/AIDS prevention and gender issues; 2) The status of HIV/AIDS and prevention strategies; 3) Some observations on the view of HIV/AIDS in Africa; 4) Using a gender perspective - gender gaps, discrimination and oppression; 5) Sharing of African prevention materials; 6) Developing gender sensitive materials; 7) Some guidelines for empowering target groups; 8) Women empowerment framework; 9) Key lessons learnt about the integration of gender into programmes; 10) Conclusion: need for gender sensitive prevention strategies.