This Guidance on HIV in Education in Emergencies provides information for education practitioners who provide, manage or support education services in emergencies. It provides guidance for mainstreaming HIV and sexual and reproductive health issues into formal and nonformal education responses for adolescents 10-19 years old. Parts 1 and 2 of this guide focus on the behavioural measures of combination prevention. Education in emergencies is about more than just providing teaching and learning of literacy and numeracy. It is a way to empower adolescents through cognitive, emotional and social learning, to help them make informed decisions and act on them. The guidance on this section can be used to inform curriculum revision or enrichment. Life skills based HIV education works best where schools and learning spaces are safe; where steps have been taken to eliminate gender inequality and discrimination, GBV and HIV-related stigma and discrimination; and where learners and staff have access to available services. Parts 3 and 4 of the guide therefore deal with the legislative, structural and biomedical measures of combination prevention that are needed to support the behavioural measures (learning and teaching).