The SADC Protocol on Health stipulates that Member States should cooperate in dealing with health issues in a harmonised manner as an essential ingredient for the effective control of communicable diseases in the region notably, HIV, TB and Malaria. As part of the response, key strategic frameworks to guide action in the control of these three diseases have been developed by SADC but these mostly address the adult population. In this context, the SADC Secretariat is mandated to develop The SADC Minimum Standards for Child and Adolescent HIV, TB and Malaria Continuum of Care. The Minimum Standards is the guideline document that establishes the minimum package of services that MS should have to achieve a common response in the region. Once harmonised, the minimum standards, when translated into policies and practice at the national level, will ensure that the SADC children population, including migrants and vulnerable population, will receive standardized HIV, TB and Malaria prevention and treatment services throughout the region. Additionally, the Minimum Standards will be profiled so that they ensure guidance in establishing the necessary links with non-clinical services platform as established in the SADC Strategic Framework and Programme of Action for Orphans and Vulnerable Children and Youth (OVCY). The first step in the articulation of this initiative was to identify the existing policies and programming frameworks in the area of child and adolescent HIV, TB and malaria, and appraise the extent to which these are integrated and harmonised in the SADC region. To this end, a regional assessment was conducted in the 14 active SADC Member States in the last quarter of 2011. Findings and results of this assessment will inform the development of the Minimum Standards for Child and Adolescent HIV, TB and Malaria Continuum of Care. This report contains the findings of the regional assessment. Its intended audience are policy makers, technical experts and implementers and other key stakeholders at national level in all Member States who can use it as a basis to explain the need and advocate for implementation of the Minimum Standards for Child and Adolescent HIV, TB and Malaria Continuum of Care and ensure the mainstreaming of these Standards into national policy documents.