The main purpose of this study is to conduct a situation-response analysis of the education sector’s response to HIV, drugs and sexual health. The objectives of this review are to: - describe and analyse the situation of HIV and AIDS, drugs and sexual health in Brunei Darussalam; - evaluate the status and scope of the education sector’s response to HIV and AIDS, drugs and sexual health; - identify the scope for improvement and prepare a set of recommendations to strengthen the existing response. In Brunei Darussalam statistical data revealed low number of HIV cases over the past 26 years. However, the report shows that the number of sexually transmitted infections (STIs) cases is increasing. Thus, more concerted efforts and collaborative partnerships between the relevant ministries and non-government organizations are needed to prevent the risky behaviour amongst the young generation.