EDC conducted this desk review to determine those elements that are essential for developing the capacity of the education sector to perform M&E activities that will strengthen country-level comprehensive responses to HIV and AIDS within a coordinated regional approach. The education sector plays an important role in the HIV and AIDS response throughout the Caribbean and M&E helps to ensure that policies, programs, and services are addressing the primary challenges and are achieving their intended results. This review seeks, also, to catalogue the availability and quality of information in guidance documents, the scientific literature, databases, and case studies and reports that inform the development of an M&E framework for the HIV response in the Caribbean education sector.