The Nutrition-Friendly Schools Initiative (NFSI), a school-based health and nutrition program is being adopted as the platform on which to implement a set of school-based health and nutrition activities aimed at improving the school environment to make it more nutrition sensitive. It is globally accepted that schools are an ideal place for children and youth to observe and learn about healthy eating and nutrition as they often eat at school or buy meals and snacks there. The NFSI hinges on four pillars: School health and nutrition guiding principle, that describes actions that school authorities agree and expect to happen in the schools; Safe school environment that ensures a food environment that promotes intake of nutritious foods and discourages serving or sale and promotion of unhealthy foods; School-based delivery of health services which focuses on providing health and nutrition services and Skills-based health education: which is centered on a behavior change approach for the promotion of optimal nutrition,sexual and reproductive health and rights, physical activity and hygiene. This guideline has been developed to provide regional education and health officers, school authorities, teachers and health workers guidance on how to implement activities to improve the nutrition environment in schools.