This booklet is the eighth in a series of publications that address key themes of UNESCO’s work in HIV and Health Education. It marks the first of several contributions to school-based health promotion that UNESCO will produce to complement our work in HIV and sexuality education. The booklet lays out the context, extent and impact of homophobic bullying and synthesizes lessons learned as well as good policies and practices for an education sector response to homophobic bullying. This booklet is intended mainly for education sector policy-makers, planners and managers. We hope it will also be useful for school governing bodies, administrators, head teachers, teachers and other educators who are tackling some of the challenges to create healthy learning environments.