This article is based on a school-based intervention which was undertaken to improve knowledge about reproduction, fertility, and contraception among adolescents in Bangladesh. The study was carried out from February 2001 to September 2002. The objective of the study was to determine the ffectiveness of school-based intervention which combined community sensitization with the distribution of three booklets addressing 1) puberty, 2) fertility and family planning, and 3) STDs/AIDS. The results of the study provide valuable information on the process of implementing a culturally-sensitive intervention. The observation identified the complexity of adolescent reproductive health interventions and the need to be flexible. This study further supports an intervention that combines community sensitization with the distribution of booklets to school-attending teenagers can effectively improve knowledge about sexual and reproductive health.