This article reports on teenage pregnancy and associated factors in Ethiopia. All studies available to the year 2020 conducted on teenage pregnancy in Ethiopia were included. The purpose of this systematic review and meta-analysis was to synthesize evidence on the prevalence and associated factors with teenage pregnancy in Ethiopia. The preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines to conduct this meta-analysis were followed by the reviewers. The pooled estimated prevalence of teenage pregnancy in Ethiopia was 23.59% (95% CI: 14.75, 32.43). Sexual practice before the age of 15 years (OR = 1.75(95%CI 1.06, 2.44), no history of contraceptive use OR =3.53 (95%CI 1.94, 5.12) and Marital status OR=2.35 (95%CI1.36, 3.34) were factors associated with teenage pregnancy. Sex education in schools and enhanced contraceptive utilization among adolescents are recommended. Future quantitative as well as qualitative researches should focus on personal as well as social determinants to teenage pregnancy.